Detalhe da pesquisa
1.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 184(18): 4651-4668.e25, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450028
2.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 187(6): 1565-1566, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490183
3.
Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.
J Physiol
; 596(3): 445-475, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023798
4.
Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches.
Bioconjug Chem
; 29(12): 3937-3966, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30265523
5.
The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system?
Acta Neuropathol
; 135(3): 387-407, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29428972
6.
On a time domain boundary integral equation formulation for acoustic scattering by rigid bodies in uniform mean flow.
J Acoust Soc Am
; 142(6): 3624, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29289087
7.
Visible and Sub-visible Particle Formation for a Model Bioconjugate.
AAPS PharmSciTech
; 18(3): 926-931, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27161337
8.
A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.
Nat Neurosci
; 26(3): 416-429, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36635496
9.
CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5053, 2023 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37598178
10.
Brain barriers virtual: an interim solution or future opportunity?
Fluids Barriers CNS
; 19(1): 19, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232464
11.
Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
J Exp Med
; 219(3)2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226042
12.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Mol Neurodegener
; 17(1): 41, 2022 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35690868
13.
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.
Sci Transl Med
; 12(545)2020 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461332
14.
Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery.
J Control Release
; 286: 467-484, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30081144
15.
Molecular characterization of perivascular drainage pathways in the murine brain.
J Cereb Blood Flow Metab
; 38(4): 669-686, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29283289
16.
Author Correction: CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5516, 2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679403
17.
Probing the extracellular diffusion of antibodies in brain using in vivo integrative optical imaging and ex vivo fluorescence imaging.
J Control Release
; 197: 78-86, 2015 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25449807
18.
Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.
J Cereb Blood Flow Metab
; 35(3): 371-81, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25492117